Rat Guanine nucleotide-binding protein G (s)subunit alpha PharmaGenie ELISA Kit (SBRS0137)

The Rat Guanine nucleotide-binding protein G(s) subunit alpha competitive ELISA from Assay Genie is configured as a 96-assay microplate kit targeting the heterotrimeric G protein alpha-s isoform encoded by the Gnas locus. The Gs alpha subunit couples ligand-activated GPCRs to adenylate cyclase, driving intracellular cAMP production, and quantitative measurement of its levels is relevant to investigations of beta-adrenergic, glucagon, parathyroid hormone and related signalling cascades.

This kit accepts cell culture supernatants as well as heparinized plasma and serum-derived fractions, providing a quantitative readout suited to studies of neuroendocrine activation, metabolic regulation and GPCR pathway pharmacology in rat models. Each kit is supplied as a complete reagent set including pre-coated plate, calibrated standards and detection antibody sufficient for 96 determinations.