Rat GRIN1/NMDAR1 ELISA Kit

From Assay Genie, this sandwich ELISA kit is designed for the quantitative measurement of GRIN1/NMDAR1 in rat samples. Reactivity is confirmed for rat, and the kit is intended for the detection of GRIN1/NMDAR1 levels in serum, plasma, cell culture supernatant, cell or tissue lysate, and other liquid samples. It uses a colorimetric, double antibody sandwich ELISA format to deliver sensitive and specific results for research applications.

Performance specifications include a sensitivity of 0.188 ng/mL and an assay range of 0.313-20 ng/mL. Reported linearity at 1:2, 1:4, and 1:8 dilutions is 83-100%, 83-99%, and 82-97% for serum (n=5); 87-95%, 83-99%, and 83-95% for EDTA plasma (n=5); and 91-102%, 83-99%, and 85-99% for heparin plasma (n=5). Recovery ranges are 88-102% (average 95%) for serum, 89-99% (average 94%) for EDTA plasma, and 86-102% (average 96%) for heparin plasma. The kit is stored at 2-8°C for 12 months.

GRIN1/NMDAR1 is an essential subunit of the N-methyl-D-aspartate (NMDA) receptor, a key player in synaptic plasticity and memory formation. Dysregulation has been linked to neurological disorders including schizophrenia, Alzheimer's disease, and epilepsy, supporting its use as a potential therapeutic target and biomarker. The kit is suited to signal transduction research and studies of neuronal function and dysfunction.