Rat Granulin (GRN) ELISA Kit

Granulin (GRN) is a secreted cysteine-rich glycoprotein linked to lysosomal homeostasis, wound healing, and microglial activation. This colorimetric ELISA from Assay Genie provides quantitative measurement of GRN in rat samples, supporting research into neurodegeneration, peripheral inflammation, and tissue-repair signaling pathways.

The kit is configured for 96 assays in a microplate format and is validated for tissue homogenates, cell lysates, and cell culture supernatants. The protocol accommodates in vivo and in vitro specimens, enabling GRN profiling across rat disease models and primary cell experiments. Output is read on a standard microplate reader.

Applications include studies of frontotemporal dementia, where progranulin haploinsufficiency contributes to lysosomal dysfunction, as well as investigations of growth-factor signaling, tumor biology, and neuroinflammation in rodent systems. The full-length progranulin protein can be processed into smaller granulin peptides with distinct biological activities. The product is supplied as a complete kit containing a microplate, standards, and detection components ready for laboratory workflows.