Rat Glycine Dehydrogenase (GLDC) ELISA Kit

Quantitative analysis of glycine dehydrogenase, the mitochondrial P-protein of the glycine cleavage system (EC 1.4.4.2), is critical for research into glycine encephalopathy, hepatic one-carbon metabolism, and tumor metabolic reprogramming. This rat GLDC ELISA kit from Assay Genie supplies the reagents needed to measure endogenous GLDC protein in experimental samples from rodent models. The enzyme, approximately 113 kDa in size, catalyzes the oxidative decarboxylation of glycine, contributing to folate-dependent one-carbon transfers and serine-glycine interconversion. Loss-of-function variants cause severe neonatal neurological disease, making the protein a focus in metabolic and neurodevelopmental research. The kit supports investigation of glycine catabolism in liver and brain tissue, mitochondrial dysfunction in cancer cells, and developmental biology studies. Each kit is supplied as a complete set of reagents including pre-coated wells, detection antibody, and standards, enabling measurement across multiple rat-derived sample types. Store refrigerated upon arrival and protect from light to preserve antibody activity; aliquot reconstituted standards to limit repeated freeze-thaw cycles. For research use only.