Rat Glutathione Reductase (GR) ELISA Kit

Assay Genie's quantitative enzyme immunoassay measures rat glutathione reductase (GR), a flavoenzyme that catalyzes the NADPH-dependent reduction of oxidized glutathione (GSSG) to its reduced form (GSH). GR sits at a pivotal node in the cellular antioxidant network, and its measurement in rat models is widely used to evaluate oxidative stress status in hepatic, renal, neural, and cardiovascular tissues.

Researchers investigating chemically induced liver injury, streptozotocin-diabetes complications, ischemia-reperfusion damage, and aging-related neurodegeneration incorporate GR quantitation as part of broader antioxidant profiling alongside markers such as glutathione peroxidase, catalase, and superoxide dismutase.

The kit is supplied as a complete package containing pre-coated microplate wells, recombinant or purified GR calibrators, horseradish peroxidase-labeled detection antibody, chromogenic substrate solution, wash buffer, and stop reagent, configured for 96 assays per kit. Sample preparation from clarified rat tissue homogenates is straightforward, and the procedure is intended for research use only in laboratory rodent studies. Each kit ships with reagents sufficient for the stated number of determinations, and the components are calibrated for absorbance readout on standard microplate readers.