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Rat Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2B (GRIN2B) ELISA Kit
  • Rat Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2B (GRIN2B) ELISA Kit
Assay Genie

Rat Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2B (GRIN2B) ELISA Kit

Price on request

SKUPriceQuantity
RTDL00459

Price on request

Description

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GRIN2B encodes the NR2B subunit of the N-methyl-D-aspartate (NMDA) receptor, an ionotropic glutamate receptor that gates calcium entry and drives excitatory synaptic transmission in the central nervous system. This assay from Assay Genie measures NR2B protein in rat tissue homogenates, cell lysates, and matched research sample preparations, and is used in neuroscience studies of long-term potentiation, learning, memory consolidation, and cortical development. The kit is applied in rodent models of neurological and psychiatric disease, including Alzheimer's-related cognitive decline, schizophrenia, temporal lobe epilepsy, ischemic stroke, and chronic neuropathic pain, where altered NMDA receptor subunit composition has been documented. Research applications extend to pharmacology, where investigators profile NR2B-selective antagonists such as ifenprodil and Ro 25-6981, and to studies of gene-environment interactions during brain development. Each kit ships with a pre-coated microplate and reagents sufficient for 96 assays, and is intended for research use only. For storage, keep sealed components refrigerated, protect the chromogen from light, and aliquot the standard to limit freeze-thaw cycles.