Rat Gastrokine 2 (GKN2) ELISA Kit

Gastrokine 2 (GKN2) is a secreted gastric mucosal protein produced by surface mucus cells, where it supports epithelial barrier maintenance, restitution after injury, and protection against luminal insults. Downregulation of GKN2 has been reported in gastric adenocarcinoma, Helicobacter pylori-associated gastritis, and intestinal-type metaplasia, positioning this analyte as a candidate biomarker for gastrointestinal oncology and mucosal inflammation studies. Investigators using this Assay Genie kit quantify endogenous GKN2 in biological specimens, profile differential expression in rat disease models, and characterize the trefoil-factor signaling axis that preserves mucosal homeostasis.

The kit includes a pre-coated microplate, lyophilized recombinant standards, biotinylated detection antibody, streptavidin-HRP conjugate, chromogenic substrate, and wash buffer for a single plate run. Unopened components should be stored at 4 °C; reconstituted standards and diluted samples are stable through limited freeze-thaw cycles when aliquoted. Intended for research use only, not for diagnostic procedures.