Rat Flt3L (FMS Like Tyrosine Kinase 3 Ligand) ELISA Kit (RTFI01476)

Flt3L is a hematopoietic cytokine that drives the expansion of myeloid and lymphoid progenitors, the maturation of dendritic cell populations, and the reconstitution of immune lineages after myeloablation. Rat models are widely used to interrogate these pathways because rodent Flt3 signaling shares conserved receptor-ligand interactions with the human system while permitting controlled in vivo perturbation. Investigators quantify circulating and tissue Flt3L to track steady-state hematopoiesis, to monitor recovery after irradiation or chemotherapy, and to characterize leukemic microenvironments in which Flt3-bearing blasts modulate stromal ligand availability.

The immunoassay is supplied as a complete kit from Assay Genie and is configured for the quantitative measurement of rat Flt3 ligand in experimental specimens. Pre-coated plate wells, matched antibody reagents, and calibrator standards are included so laboratories can run unknowns alongside a standard curve for direct interpolation of analyte concentrations. The assay fits typical workflows that already include a microplate reader capable of absorbance measurements, and the reagents are intended for research use only. Common downstream applications include correlating bone marrow cellularity with circulating ligand, profiling Flt3L dynamics during graft-versus-host studies, and comparing expression across in vivo treatment cohorts.