Rat Fibrinogen Like Protein 2 (FGL2) ELISA Kit

Quantitative measurement of fibrinogen-like protein 2 in rat plasma samples is supported by this immunoassay kit from Assay Genie, which targets a pleiotropic effector molecule implicated in coagulation cascades, angiogenesis, and immune regulation. The assay equips researchers investigating transplant tolerance, viral pathogenesis, and autoimmune inflammation with a reproducible workflow to monitor circulating soluble FGL2 levels in experimental rodent models.

FGL2, also referenced in the literature as prothrombinase or fibroleukin depending on isoform context, is secreted by activated macrophages and endothelial cells. The soluble form suppresses T-cell proliferation through engagement of FcγRIIB receptors on responder lymphocytes, shaping cytokine balance and contributing to maternal-fetal tolerance. Quantifying its plasma concentration supports studies of hepatic inflammation, alloimmune responses, and Th1/Th2 polarization in rats.

Each package includes reagents sufficient for 96 assays configured in a microplate layout, accommodating batched experimental runs. The kit is intended for research use only, with an absorbance-based readout obtained on a standard laboratory plate reader. Reagents should be stored refrigerated between uses to preserve activity through repeated freeze-thaw cycles if applicable to individual components.