Rat Cold-inducible RNA-binding protein (Cirbp) ELISA Kit

This Sandwich ELISA kit from Assay Genie is designed for the quantitative measurement of rat Cold-inducible RNA-binding protein (Cirbp), also referred to as A18 hnRNP or Glycine-rich RNA-binding protein CIRP. Intended for research use only, it is reactive with rat samples, including serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.

The assay uses a colorimetric detection method with a detection range of 78-5000pg/ml and a sensitivity of 39.3pg/mL. Reported precision values are 5.3% intra-assay CV and 8.1% inter-assay CV. Specificity has been confirmed for natural and recombinant rat Cold-inducible RNA-binding protein. The kit is classified under the epigenetics research area. Cirbp is described as a cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival, acts as a translational activator and repressor, binds specifically to the 3'-untranslated regions of stress-responsive transcripts RPA2 and TXN, and promotes assembly of stress granules when overexpressed.