Rat Coagulation Factor XI (F11) ELISA Kit

This ELISA-format immunoassay from Assay Genie enables quantitative measurement of Coagulation Factor XI (F11), a plasma serine protease central to the intrinsic coagulation cascade, in rat-derived samples. Factor XI circulates as a homodimer of roughly 160 kDa that, once activated by thrombin or Factor XIIa, propagates coagulation by cleaving Factor IX, making it a key target for studies on hemostasis, contact pathway activation, and thrombosis models.

Developed for laboratory research applications, this in vitro kit supports investigation of FXI inhibitors, deep vein thrombosis mechanisms, and the role of FXI in inflammation-driven coagulation. Researchers can analyze plasma and related liquid specimens using a microplate-based procedure that accommodates ninety-six determinations per kit, with pre-coated wells, detection reagents, and a calibration standard sufficient to establish a dose-response curve.

All reagents are validated for rat sample compatibility, supporting reproducibility in studies of hemophilia C, liver-related coagulopathies, and contact activation pathways. Intended for research use only; not for diagnostic procedures.