Rat Cluster Of Differentiation 14 (CD14) ELISA Kit

CD14 is a glycosylphosphatidylinositol-anchored pattern recognition receptor expressed predominantly on monocytes, macrophages, and neutrophils, where it binds lipopolysaccharide (LPS) complexed with LPS-binding protein to initiate innate immune signaling through Toll-like receptor 4. Measuring soluble CD14 (sCD14) in rat serum is widely used to monitor systemic inflammation, sepsis severity, endotoxemia models, and macrophage activation in pharmacology and toxicology research. This Assay Genie ELISA kit supports quantitative in vitro detection across multiple sample matrices including tissue homogenates, enabling researchers to track CD14 expression changes in target organs as well as in circulation. Reagents are supplied in single-use vials and should be refrigerated upon arrival; reconstituted standards should be aliquoted to limit freeze-thaw cycles and preserve the stated shelf life.