Rat CHRM2/Muscarinic Acetylcholine Receptor M2 ELISA Kit

From Assay Genie, the Rat CHRM2 (Muscarinic Acetylcholine Receptor M2) ELISA Kit is a Sandwich ELISA using a double-antibody format with colorimetric detection, intended for quantitative measurement of CHRM2 in rat samples. Validated sample types include serum, plasma, cell culture supernatant, cell or tissue lysate, and other liquid samples. The kit reports a sensitivity of 37.5 pmol/mL and an assay range of 62.5–4000 pmol/mL, with stated storage at 2–8°C for 12 months.

Linearity data are reported for serum, EDTA plasma and heparin plasma at 1:2, 1:4 and 1:8 dilutions (n = 5), with recovery ranges of 93–104% in serum (average 99%), 87–105% in EDTA plasma (average 97%) and 86–105% in heparin plasma (average 96%). CHRM2 is a muscarinic acetylcholine receptor involved in cholinergic neurotransmission, with dysregulation reported in connection with conditions such as Alzheimer's disease, schizophrenia, and movement disorders.