Rat Caspase 1 (CASP1) ELISA Kit

Caspase 1 (CASP1) is a cysteine-aspartic protease that initiates inflammatory signaling by cleaving pro-IL-1β and pro-IL-18 into their mature, secreted cytokine forms. It sits at the heart of inflammasome assembly and pyroptotic cell death, two pathways examined in research on innate immunity, neurodegeneration, metabolic inflammation, and acute tissue injury. This Assay Genie ELISA enables quantitative measurement of CASP1 protein in rat-derived samples and is configured as a 96 assays kit for use with standard microplate readers.

The kit is validated for rat reactivity and is intended for research use only, supporting applications such as inflammasome activation studies, drug efficacy screening in rodent models, and characterization of caspase-driven signaling pathways in disease research. Sample types include tissue homogenates and cell lysates prepared from rat sources, applicable to both in vitro cell-based experiments and ex vivo tissue analyses.

Detection is performed by colorimetric readout, allowing straightforward quantification on laboratory plate readers commonly found in immunology, pharmacology, and cell biology facilities. Researchers studying pyroptosis, IL-1β maturation, NLRP3 inflammasome activity, or inflammatory caspase function in rat model systems will find this CASP1 ELISA a practical tool for protein-level quantification across experimental conditions.