Rat Bone Morphogenetic Protein Receptor 1A (BMPR1A) ELISA Kit

Signaling through the BMP pathway governs osteogenesis, chondrogenesis, neural patterning, and vascular development, with BMPR1A (Bone Morphogenetic Protein Receptor Type 1A, also called Activin Receptor-Like Kinase-3 / ALK-3) acting as a key transmembrane serine/threonine kinase receptor. This ELISA kit from Assay Genie enables quantitative measurement of rat BMPR1A in tissue homogenates, supporting research into skeletal biology, fracture healing, and juvenile polyposis syndrome, where germline BMPR1A variants have been identified.

The rat-reactive assay accepts tissue homogenates as input and produces a colorimetric signal compatible with standard microplate readers. Supplied in a 96-assay configuration, the kit supports laboratory studies of receptor expression in rodent experimental systems and downstream BMP pathway activity in bone and cartilage.

Applications include profiling BMPR1A expression in osteoblast and chondrocyte cultures, characterising receptor levels in bone and cartilage tissue lysates, and supporting translational investigations of germline variants implicated in hereditary polyposis. The kit is intended for research use only.