Rat ALPL (Alkaline Phosphatase, Liver/Bone/Kidney) ELISA Kit (RTES00914)

The Assay Genie rat ALPL enzyme-linked immunosorbent assay kit delivers a quantitative measurement platform for tissue-nonspecific alkaline phosphatase in laboratory rat specimens. ALPL, the protein product of the Alpl gene, is a membrane-bound glycosylated enzyme expressed across liver, bone, and kidney tissue, where it supports bone mineralization and phosphate metabolism.

Each kit supplies reagents configured for 96 individual determinations, packaged in vials together with a pre-coated microplate holding capture antibodies specific to the rat ALPL isozyme. The in vitro immunoassay protocol is compatible with liquid samples prepared from rat sources, and each component is labelled for research use only. Detailed buffer preparation, incubation times, and washing parameters are documented in the enclosed product insert.

Investigators in bone biology, hepatology, and toxicology use this reagent to track osteoblast activity, hepatic injury markers, and renal function in rat preclinical models. ALPL also serves as a clinically relevant biomarker for hypophosphatasia, Paget's disease of bone, and other mineralization disorders, supporting osteoporosis research and longitudinal drug-response studies.