Rat Adenomatous polyposis coli protein (Apc) ELISA Kit

From Assay Genie, this Sandwich ELISA kit is designed to detect and quantify rat Adenomatous polyposis coli protein (Apc) in biological samples. The assay uses ELISA-based detection and has been validated for reactivity with rat samples, with specificity for natural and recombinant rat Adenomatous polyposis coli protein.

Validated sample types include serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. Reported performance specifications include a detection range of 78-5000pg/mL and a sensitivity of 39.21pg/mL. Precision is reported as an intra-assay CV of 3.7% and an inter-assay CV of 7.0%. Linearity has been evaluated in serum, EDTA plasma and heparin plasma across dilutions of 1:2, 1:4, 1:8 and 1:16, and recovery ranges from 89-101% in serum and 91-103% in plasma.

Adenomatous Polyposis Coli (APC) functions as a tumour suppressor involved in the regulation of cell growth and division. Mutations in the APC gene are commonly found in cancers such as colorectal cancer, making it a significant biomarker for cancer research. The kit is intended for research use only and is associated with Uniprot accession P70478.