Rat 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR) ELISA Kit

3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR) catalyzes the conversion of HMG-CoA to mevalonate, the committed and rate-limiting step of cholesterol biosynthesis, and is the established pharmacological target of statin drugs used clinically to lower circulating LDL cholesterol. Provided by Assay Genie, this colorimetric microplate assay enables quantitative measurement of HMGCR protein in rat tissues and cell lysates, supporting research into hepatic lipid metabolism, statin mechanism-of-action studies, and rodent models of dyslipidemia and atherosclerosis.

Reconstituted standards and detection antibody should be aliquoted and stored at -20°C to preserve activity through repeated freeze-thaw cycles, while the sealed plate and lyophilized reagents remain stable for the shelf life of the kit when refrigerated.