Rabbit Aggrecan (AGC) ELISA Kit

Quantitative measurement of aggrecan (AGC), a large chondroitin sulfate proteoglycan that forms the load-bearing backbone of articular cartilage, is supported by this immunoassay from Assay Genie for use with rabbit-derived specimens in cartilage biology and osteoarthritis research. Aggrecan is a major structural component of the cartilage extracellular matrix, where it interacts with hyaluronan to form aggregates that resist compression; quantifying circulating aggrecan levels supports studies of cartilage turnover, joint degeneration, and regenerative interventions in rabbit joint disease models.

Each package contains reagents sufficient for 96 individual determinations, supplied in vials and microplate wells for reconstitution. The assay is configured for in vitro research use only and is intended for laboratory personnel familiar with plate-based immunological detection workflows. Researchers employing rabbit models of joint pathology — including anterior cruciate ligament transection, meniscal tear induction, and pharmacologic chondroprotection studies — can apply the kit to monitor cartilage matrix biomarkers during longitudinal interventions.

Storage and handling should follow the package insert accompanying the kit; unopened components are commonly refrigerated, substrate solutions should be shielded from light, and reagents equilibrated to room temperature before each run. Repeated freeze-thaw cycles of reconstituted standards and prepared specimens should be avoided to maintain epitope integrity. As part of translational cartilage research and comparative orthopaedics workflows, the Assay Genie Rabbit Aggrecan (AGC) ELISA Kit provides a species-matched detection option for studies requiring rabbit-reactive reagents.