Porcine Vascular endothelial growth factor A (VEGFA) ELISA Kit

From Assay Genie, this Sandwich ELISA kit is designed for the precise measurement of Vascular endothelial Growth Factor A (VEGFA) in porcine samples, offering high sensitivity and specificity for a variety of research settings. The kit detects both natural and recombinant pig VEGFA, a key growth factor that is active in angiogenesis, vasculogenesis and endothelial cell growth. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.

According to the manufacturer specification, the detection range is 31.2-2000pg/mL with a sensitivity of 8.3pg/mL. The kit is reactive with porcine (pig) samples and is suitable for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The detection method is colorimetric. VEGF-related work with this kit falls within the cancer research area.

The target protein is a homodimer that is disulfide-linked and is localised to the secreted compartment of the cell, although it remains associated with cells or to the extracellular matrix unless released by heparin. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin, and interacts with NRP1. The UniProt accession is P49151, and the protein is also known by synonyms including Vascular permeability factor, VPF, VEGF-A and VEGF.