Pim Kinase ELISA Sampler Kit

Pim kinases (Pim-1, Pim-2, and Pim-3) constitute a family of constitutively active serine/threonine kinases that govern cell-cycle progression, anti-apoptotic signaling, and transcriptional control, with abnormal expression implicated in B-cell lymphomas, prostate cancer, hepatocellular carcinoma, and cytokine-driven cardiac hypertrophy.

The Assay Genie Pim Kinase ELISA Sampler Kit consolidates four independent 48-assay plates into a single pack, enabling laboratories to quantify multiple Pim family members from parallel aliquots of the same donor set without sourcing each isoform-specific kit separately. Each plate is pre-coated with an isoform-selective capture antibody, and bound analyte is revealed through an enzyme-linked reporter and chromogenic readout captured on a standard microplate reader.

Investigators in translational oncology, immune signaling research, and cardioprotection deploy this sampler pack to track baseline expression and treatment-induced modulation of Pim kinase activity in human research samples, supporting pharmacodynamic biomarker work and small-molecule Pim inhibitor screening programs. Reagents sufficient to complete all four runs are supplied, including coated plates, calibrator proteins, reporter conjugate, wash buffer, and substrate solution, with the package intended for research use only.