NRL Transcription Factor Activity Assay

A DNA-binding transcription factor activity kit from Assay Genie quantifies activated Neural Retina Leucine Zipper (NRL) protein in nuclear and cell lysates using a colorimetric method read on a standard microplate. NRL drives rod photoreceptor differentiation and rhodopsin expression, and the assay is built to measure its functional DNA-binding activity rather than total protein abundance. Researchers in vision science and retinal development use the strip-plate format to profile NRL activation across Human, Mouse, and Rat samples, supporting studies of inherited retinal degenerations, photoreceptor maturation, and gene regulatory networks in ocular disease. The kit provides reagents for 96 reactions and is configured for research use only, with binding activity reported in relative absorbance units.