N (6)-Carboxymethyllysine (CML) ELISA Kit

From Assay Genie, this Competitive ELISA Kit is designed for the accurate quantification of N(6)-Carboxymethyllysine (CML), an advanced glycation end product (AGE) that forms as a result of non-enzymatic glycation and oxidation of proteins. The kit is intended for research use only and is suitable for use with serum, plasma, and tissue culture supernatants.

Elevated levels of CML have been associated with various pathological conditions, including diabetes, cardiovascular diseases, and neurodegenerative disorders. By measuring CML levels accurately, researchers can gain insights into the role of AGEs in disease progression and potentially develop new therapeutic strategies.

The assay uses a colorimetric, competitive detection method with a quantitative range of 0.78-50 ng/mL. Optical density values are determined using a microplate reader set to 450 nm.