Mouse Zinc transporter 8 (Slc30a8) ELISA Kit

A sandwich ELISA kit from Assay Genie designed for the quantitative measurement of mouse Zinc transporter 8 (SLC30A8), also referenced by the synonyms Solute carrier family 30 member 8, ZnT-8, and Znt8. The assay is reactive with mouse samples and is run as a colorimetric detection method.

According to the manufacturer's datasheet, the kit has a detection range of 0.78-50ng/mL and a sensitivity of 0.422ng/mL. It is intended for use with serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. Specificity is reported for natural and recombinant mouse Zinc transporter 8, and the target functions as a homodimer associated with the insulin and glucagon secretory granules at the cell membrane and secretory vesicle membrane (UniProt Q8BGG0).

SLC30A8 is described as a key transporter protein that plays a critical role in zinc homeostasis and insulin storage in pancreatic beta cells, and its dysregulation has been implicated in the development of type 2 diabetes. The kit is positioned for research into metabolism and related metabolic disorders and is designated for research use only.