Mouse X-Ray Repair Cross Complementing 6 (XRCC6) ELISA Kit

XRCC6, also known as Ku70, is a 70 kDa ATP-dependent DNA helicase that forms a heterodimer with XRCC5 (Ku80) and drives non-homologous end joining (NHEJ), the predominant pathway for repairing DNA double-strand breaks in mammalian cells. This Mouse XRCC6 ELISA Kit from Assay Genie enables quantitative measurement of endogenous Ku70 protein in tissue homogenates, supporting research into genomic instability, radiation response, V(D)J recombination, telomere maintenance, and tumor biology. The kit includes a microplate pre-coated with a mouse-specific capture antibody, along with lyophilized standards, detection antibody, and buffers supplied ready-to-use. A TMB substrate generates the readout, with a 100 µL sample volume per well and a typical run time under three hours. Researchers studying DNA damage signaling, chemoresistance, or transgenic and knockout mouse models commonly use this kit to compare Ku70 expression across genotypes, tissues, or treatment conditions.