Mouse Von Hippel-Lindau disease tumor suppressor (Vhl) ELISA Kit

Assay Genie offers a sandwich ELISA kit for quantitative detection of mouse Von Hippel-Lindau disease tumor suppressor (Vhl) in research samples. The colorimetric assay is validated for mouse reactivity and accepts serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. Specificity covers both natural and recombinant mouse Vhl, with the protein also referenced under the synonyms pVHL and Vhlh.

Vhl is a tumour suppressor that regulates cell growth and division, oxygen sensing and angiogenesis; mutations in the Vhl gene are associated with Von Hippel-Lindau disease, a rare genetic disorder characterised by tumour development across multiple organs. The manufacturer reports a detection range of 0.156-10ng/mL and a sensitivity of 0.086ng/mL. The protein (UniProt P40338) localises to the cytoplasm, peripheral membrane and nucleus, and is studied within the cancer research area. Intra-assay CV, inter-assay CV, linearity and recovery values are supplied with the kit; for research use only.