Mouse Vinculin (Vcl) ELISA Kit

A sandwich-format ELISA for the quantitative measurement of mouse Vinculin (Vcl), supplied by Assay Genie. The kit is designed for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and shows reactivity with mouse samples. Specificity covers natural and recombinant mouse Vinculin, with Metavinculin listed as a synonym, and detection is by a colorimetric method.

The reported detection range is 1.56-100ng/mL with a sensitivity of 0.78ng/mL. Vinculin is described as an actin filament (F-actin)-binding protein involved in cell-matrix and cell-cell adhesion, where it regulates cell-surface E-cadherin expression and may play important roles in cell morphology and locomotion. The research area noted is cardiovascular, the associated UniProt entry is Q64727 with a molecular weight of 116,717 Da, and subcellular localisation includes the cell membrane (cytoplasmic side), cell junctions, adherens junctions, focal adhesions, cytoplasm and cytoskeleton. For research use only.