Mouse V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) ELISA Kit

Quantify mouse ErbB3 (HER3) protein levels with this quantitative immunoassay from Assay Genie, intended for measurement in mouse-derived research samples. ErbB3 is a member of the ErbB receptor tyrosine kinase family that lacks strong intrinsic kinase activity and signals primarily through heterodimerization with ErbB2, activating downstream PI3K/AKT and MAPK pathways implicated in cardiac neural crest development, Schwann cell myelination, and ErbB2-driven tumor progression in mouse models. Investigators studying neuregulin-1 (NRG1) signaling, breast cancer xenografts, or cardiac cushion formation apply this mouse ErbB3 ELISA to assess receptor expression in liquid biological specimens and tissue homogenate preparations from mouse sources. The kit is supplied as 96 assays in a microplate format with all required reagents, producing an absorbance-based readout measurable on a standard plate reader. For research use only; not for diagnostic procedures. Reconstituted standards and detection components should be kept refrigerated between uses to preserve activity across freeze-thaw cycles.