Mouse Utrophin (UTRN) ELISA Kit

Utrophin (UTRN) is a large cytoskeletal protein closely related to dystrophin, widely studied in neuromuscular research, particularly as a compensatory analogue in Duchenne muscular dystrophy mouse models. This colorimetric ELISA from Assay Genie enables quantitative measurement of mouse UTRN in research sample types such as tissue homogenates and cell lysates, supporting investigations of sarcolemmal stability, muscle regeneration, and gene-therapy response monitoring.

The microplate-format assay is intended for research use only, with reagents optimized for in vitro quantification of native mouse utrophin. Researchers commonly apply this kit to skeletal muscle, cardiac, and neural tissue preparations, where utrophin expression serves as a biomarker of dystrophin deficiency and as a readout for therapeutic strategies aimed at upregulating UTRN transcription.

Each kit supplies the components required to run the immunoassay workflow, including a pre-coated plate, standard, detection antibody, and substrate. The standard protocol involves adding standards and samples to coated wells, performing the binding incubation, washing, adding detection reagent, and reading absorbance to interpolate utrophin concentration (typically reported in ng/mL) against the standard curve.