Mouse UDP-glucuronosyltransferase 1-1 (Ugt1a1) ELISA Kit

Designed for the accurate quantification of UDP-glucuronosyltransferase 1-1 (UGT1A1) levels in mouse samples, this colorimetric Sandwich ELISA Kit from Assay Genie provides researchers with a reliable tool for studying liver physiology, drug metabolism, and toxicology. UGT1A1 is an important liver enzyme involved in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds, playing a critical role in the metabolism of bilirubin, drugs, and other substances.

The kit has a detection range of 78-5000pg/mL and a sensitivity of 39.4pg/mL, with an intra-assay CV of 6.9% and inter-assay CV of 9.3%. It is validated for use with serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids, and shows specificity for natural and recombinant mouse UDP-glucuronosyltransferase 1-1.

Recovery is reported as 107% (range 101-113%) for serum and 109% (range 103-115%) for plasma. Linearity in serum ranges from 88-100% at 1:2 dilution to 99-109% at 1:16 dilution. The target protein has a molecular weight of 58 kDa (UniProt Q63886, NCBI Gene ID 394436) and is also known by the synonyms UDP-glucuronosyltransferase 1A1, UGTBR1, UDPGT 1-1, and Ugt1. For research use only.