Mouse UDP Glucose Ceramide Glucosyltransferase (UGCG) ELISA Kit

This ELISA kit from Assay Genie quantifies UDP-glucose ceramide glucosyltransferase (UGCG) in mouse-derived samples, targeting a Golgi-resident enzyme that catalyzes the conversion of ceramide to glucosylceramide, the rate-limiting first glycosylation step in glycosphingolipid biosynthesis.

UGCG expression is relevant to cancer drug resistance research, where elevated glucosylceramide pools have been linked to chemotherapy efflux in tumor cells, and to neurodegenerative disease models where sphingolipid dysregulation contributes to pathology. The assay accepts tissue homogenates and cell lysates prepared from mouse specimens, supporting work in liver, brain, spleen, kidney, and cultured cell systems. Researchers employ it in vitro to monitor enzyme abundance across experimental treatments and in vivo to compare UGCG levels between wild-type and genetically modified mouse strains.

Each kit contains a pre-coated microplate, calibrated standards, detection antibody, wash buffer, substrate, and stop solution, providing reagents for one full plate run. Storage requirements and the expiration date appear on the enclosed product insert. The product is labeled for research use only and is not validated for clinical diagnostic procedures.