Mouse UCHL1 ELISA Kit

Assay Genie provides a Sandwich ELISA kit designed for the accurate quantification of UCHL1 (Ubiquitin carboxyl-terminal hydrolase isozyme L1) levels in mouse samples. UCHL1 is a key enzyme involved in the regulation of protein degradation and maintenance of neuronal function, and its dysregulation has been linked to various neurodegenerative disorders, making it a critical biomarker for studying these conditions and potential therapeutic interventions.

The assay uses a double antibody sandwich format with colorimetric detection and is validated for serum, plasma, cell culture supernatant, cell or tissue lysate, and other liquid samples. The kit demonstrates a sensitivity of 37.5 pg/mL and a measurement range of 62.5-4000 pg/mL. Validated linearity spans 80-105% across serum, EDTA plasma, and heparin plasma at 1:2, 1:4, and 1:8 dilutions (n = 5), while recovery averages 94-95% across the same sample types (n = 5).

Storage is recommended at 2-8°C for 12 months. The associated UniProt identifier is Q9R0P9, and the protein is also known by synonyms including PARK5, PGP9.5, and ubiquitin carboxyl-terminal hydrolase isozyme L1. Researchers investigating UCHL1 in neurodegenerative disease models will find this kit a reliable tool for reproducible results.