Mouse TYR (Tyrosinase) ELISA Kit (MOES01601)

Tyrosinase (TYR) is a copper-containing metalloenzyme that catalyzes the rate-limiting steps in melanin biosynthesis, converting L-tyrosine to L-DOPA and subsequently to DOPAquinone.

The Assay Genie Mouse TYR ELISA Kit is an in vitro research tool for quantifying tyrosinase levels in mouse-derived samples, supporting studies in melanogenesis, melanocyte biology, pigmentation disorders, and melanoma research. Tyrosinase activity and expression are central to investigations of vitiligo, albinism, and cutaneous melanoma progression, where this enzyme serves as both a differentiation marker for melanocytes and a clinically relevant tumor-associated antigen.

The kit format provides 96 individual assays for laboratory quantification workflows. Tyrosinase is also studied in the context of ocular pigmentation, hair follicle melanogenesis, and as a target in dendritic cell immunotherapy research for melanoma. Researchers using this ELISA examine TYR levels in C57BL/6 mouse models, transgenic strains with pigmentation phenotypes, and cell lines such as B16 melanoma cells, with applications spanning dermatology, oncology, neuroscience (substantia nigra dopaminergic neuron studies), and developmental biology research.