Mouse Type-2 angiotensin II receptor (Agtr2) ELISA Kit

A research-use-only Sandwich ELISA Kit from Assay Genie, designed for the accurate measurement of Type-2 angiotensin II receptor (AGTR2) levels in mouse samples. The kit, also known under the synonyms Angiotensin II type-2 receptor and AT2, provides high sensitivity and specificity for reliable quantification of both natural and recombinant mouse Type-2 angiotensin II receptor.

Performance is characterised by a detection range of 15.6-1000pg/mL and a sensitivity of 8.06pg/mL. Compatible sample types include serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, supporting studies in the research area of cancer as well as investigations into hypertension, heart disease and kidney disorders, where AGTR2 plays a key role in regulating blood pressure, vascular tone and cardiovascular function.

The target protein functions as a receptor for angiotensin II and cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. It is associated with UniProt entry P35374, has a molecular weight of 41,374 Da, and is a multi-pass membrane protein localised to the cell membrane. Supplied kit components include the ELISA microplate, lyophilised standard, sample and assay diluents, detection reagents, wash buffer, substrate, stop solution and plate sealer, with individual components stored at -20°C and 4°C.