Mouse Type-1A angiotensin II receptor (Agtr1a) ELISA Kit

Designed for the accurate detection of AGTR1A levels in mouse samples, this Sandwich ELISA kit from Assay Genie is intended for research applications in cardiovascular biology. AGTR1A is a key receptor involved in the renin-angiotensin system, playing a role in regulating blood pressure and vascular function, and its dysregulation has been linked to various cardiovascular diseases, making it an important biomarker for the study of these conditions and for the development of potential therapies.

The assay offers high sensitivity and specificity for natural and recombinant mouse Type-1A angiotensin II receptor, and is suitable for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. Reported detection range is 78-5000pg/ml with a sensitivity of 42.5pg/mL. Intra-assay CV is 6.9% and inter-assay CV is 8.8%. The associated UniProt entry is P29754 and the protein is a multi-pass cell membrane receptor for angiotensin II.

Linearity has been evaluated at dilutions of 1:2, 1:4, 1:8 and 1:16 in serum (92-101%, 81-91%, 107-117%, 85-97%), EDTA plasma (109-119%, 104-114%, 97-105%, 105-115%) and heparin plasma (88-96%, 91-91%, 102-111%, 87-95%). Average recovery is 106% (range 100-112%) for serum and 108% (range 102-114%) for plasma. Synonyms include Angiotensin II type-1A receptor, AT1A and Agtr1. For research use only.