Mouse Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) ELISA Kit

Manufactured by Assay Genie, this Mouse TNFRSF1A ELISA Kit is a sandwich-format immunoassay for the quantitative detection of tumor necrosis factor receptor superfamily member 1A in mouse samples. The assay is validated for serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids, and recognises both natural and recombinant mouse TNFRSF1A. Also referred to by synonyms including TNF-R1, TNF-RI, p55, p60, CD120a, and Tnfr-1, TNFRSF1A is a single-pass type I membrane protein localised to the cell membrane and Golgi apparatus membrane that participates in TNF-alpha signalling via the adapter FADD and caspase-8.

Reported performance characteristics include a detection range of 0.078–5 ng/ml, a sensitivity of 0.039 ng/mL, an intra-assay CV of 6.4%, and an inter-assay CV of 8.9%. Spike-and-recovery has been demonstrated in serum (average 82%, range 80–88%) and plasma (average 84%, range 80–90%). The associated UniProt entry is P25118 (NCBI Gene ID: 21937), with a reported molecular weight of 50,130 Da. The kit is intended for research use only and is classified within the neurosciences research area.