Mouse Tumor necrosis factor receptor superfamily member 13C (Tnfrsf13c) ELISA Kit

Assay Genie supplies this sandwich-format ELISA kit for the quantitative detection of mouse Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), a protein also referred to as BAFF receptor, BAFF-R, and CD268. The colorimetric assay is intended for research use only and has been validated for serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids, specifically recognizing natural and recombinant mouse TNFRSF13C.

Working performance data from the manufacturer report a detection range of 0.156–10 ng/mL and a sensitivity of 0.078 ng/mL, with absorbance read at 450 nm on a standard microplate reader. TNFRSF13C is described as a single-pass type III membrane protein that acts as the B-cell-specific receptor for TNFSF13B/TALL1/BAFF/BLyS, supporting the survival of mature B cells and contributing to the B-cell response.

In the supplied background, defects in TNFRSF13C are linked to common variable immunodeficiency type 4 (CVID4), a primary antibody deficiency, and the marker is positioned for research areas that include cancer and broader studies of inflammatory and immune-related disease mechanisms.