Mouse Tumor necrosis factor receptor superfamily member 13B (Tnfrsf13b) ELISA Kit

This Sandwich ELISA kit from Assay Genie is designed for the quantitative measurement of mouse Tumor necrosis factor receptor superfamily member 13B (Tnfrsf13b), also known as TACI, CD267, and Transmembrane activator and CAML interactor. The assay uses a colorimetric detection method and reacts with mouse samples, validated for use with serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. The kit specifically detects natural and recombinant mouse Tnfrsf13B.

The kit offers a detection range of 0.156-10ng/mL and a sensitivity of 0.086ng/mL. The target protein (UniProt Q9ET35) functions as a receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS, binding both ligands with similar high affinity. It mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1, and is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. The protein is described as a single-pass type III membrane protein located in the membrane, and binds TRAF2, TRAF5 and TRAF6.

For research use only, this kit supports studies within the cancer research area.