Mouse Transglutaminase 1, Keratinocyte (TGM1) ELISA Kit

The Mouse TGM1 (Keratinocyte Transglutaminase) ELISA Kit from Assay Genie is a quantitative immunoassay developed for research on epidermal differentiation and cornified envelope formation in murine skin biology. The enzyme encoded by the Tgm1 gene catalyzes calcium-dependent cross-linking of structural proteins during the terminal stages of keratinocyte maturation, and altered expression is investigated in models of barrier dysfunction, inflammatory skin conditions, and congenital ichthyosis research.

This microplate-based assay uses a colorimetric readout, and the kit is configured as a complete system including pre-coated plate, detection antibodies, standards, and buffer reagents. Each kit provides sufficient reagents for 96 individual determinations and is supplied for research use only, intended for in vitro laboratory work on mouse-derived samples including tissue homogenates. Components are shipped refrigerated and should be stored according to the package insert to preserve standard curve integrity.

Investigators in dermatology, epidermal barrier function, and skin pharmacology programs use this kit to quantify TGM1 protein levels across experimental conditions, supporting studies of stratum corneum development and the molecular pathology of scaling disorders such as lamellar ichthyosis.