Mouse Transcription factor AP-2-beta (Tfap2b) ELISA Kit

This Sandwich ELISA Kit from Assay Genie is designed for the quantitative detection of mouse Transcription factor AP-2-beta (Tfap2b), also known as Activating enhancer-binding protein 2-beta, AP2-beta, and Tcfap2b. The assay is intended for research use only and has a stated detection range of 1.56-100ng/mL with a sensitivity of 0.786ng/mL.

The kit has been validated for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and shows specificity for natural and recombinant mouse Transcription factor AP-2-beta. Intra-assay CV, inter-assay CV, linearity and recovery information are provided with the kit. The associated research area is cancer, and the target protein is localised to the nucleus with a reported molecular weight of 50,373 Da (UniProt Q61313).

Transcription factor AP-2-beta is a sequence-specific DNA-binding protein that binds the consensus sequence 5'-GCCNNNGGC-3' and regulates transcription of selected genes. It functions as a dimer, forming homodimers or heterodimers with other AP-2 family members, and is described as a regulator of eye, face, body wall, limb and neural tube development, with a role in proper terminal differentiation and function of renal tubular epithelia.