Mouse Transcobalamin-2 (Tcn2) ELISA Kit

From Assay Genie, this Sandwich ELISA Kit uses colorimetric detection for the quantitative measurement of Transcobalamin-2 in mouse samples. Transcobalamin-2 is the primary vitamin B12-binding and transport protein that delivers cobalamin to cells, and the assay detects both natural and recombinant mouse protein. The kit is suitable for serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. Its dysregulation has been linked to conditions such as anemia, neurological disorders, and metabolic diseases, making it a relevant biomarker for disease monitoring and therapeutic development research.

Manufacturer-reported performance characteristics include a detection range of 0.156-10ng/mL, a sensitivity of 0.078ng/mL, an intra-assay CV of 6.2%, and an inter-assay CV of 8.5%. Linearity has been evaluated in serum, EDTA plasma, and heparin plasma at dilutions of 1:2, 1:4, 1:8, and 1:16. Reported recovery is 80-89% in serum (average 83%) and 80-91% in plasma (average 85%). Synonyms for the target include Transcobalamin II, TC II, and TC-2; the protein is secreted, interacts with CD320 via LDL-receptor class A domains, and corresponds to the Tcn2 gene (UniProt O88968) with a molecular weight of 47,586 Da. The kit is listed under the Signal Transduction research area and is for research use only.