Mouse TP53 (Tumor Protein 53) ELISA Kit (MOES01599)

This 96 assays-format Assay Genie kit is configured for mouse reactivity and provides quantitative measurement of the p53 tumor suppressor protein encoded by the TP53 gene. The p53 protein sits at the center of cellular stress-response networks, coordinating cell cycle arrest, DNA repair, senescence, and apoptosis following genotoxic or oncogenic insult, and its dysregulation is a hallmark of nearly every major cancer type.

Researchers use the kit to support cancer biology studies, investigations of chemotherapy-induced DNA damage signaling, and characterization of tumor suppressor pathways in rodent disease models, including xenograft and genetically modified systems. Common experimental contexts include tracking p53 induction after genotoxic challenge, comparing basal and stress-induced p53 expression between wild-type and mutant mouse strains, profiling tumor progression in vivo, and evaluating candidate therapeutics that target the p53 pathway or its upstream regulators and downstream effectors.

Supplied as a complete ELISA package with pre-coated plate wells and the standards needed to build a standard curve, the kit yields absolute concentration readouts rather than purely relative comparisons. By enabling reproducible p53 quantification across multiple mouse-derived sample types, the kit supports both targeted mechanistic studies and larger cohort analyses examining how this critical tumor suppressor behaves under physiological, pathological, and pharmacological conditions.