Mouse TIMP-3 (Tissue Inhibitors of Metalloproteinase 3) ELISA Kit (MOES01567)

A quantitative ELISA kit from Assay Genie for measuring Tissue Inhibitor of Metalloproteinase 3 (TIMP-3) in murine research samples. TIMP-3 is unique among TIMP family members in being tightly anchored to the extracellular matrix, where it acts as a broad-spectrum inhibitor of both matrix metalloproteinases (MMPs) and several ADAM and ADAMTS metalloproteinases. This distinct binding behavior makes TIMP-3 a critical regulator of pericellular proteolysis rather than a freely circulating inhibitor.

This 96-assay kit is configured with mouse-specific reactivity and uses a colorimetric readout that runs on standard laboratory microplate readers. Researchers apply it to studies of extracellular matrix turnover in cardiac fibrosis, renal injury, osteoarthritis, tumor-stroma interactions, and chronic inflammation, where the balance between TIMP-3 and active MMPs shapes tissue remodeling outcomes.

The kit supplies the components needed for the full 96-well plate format, supporting longitudinal tracking of TIMP-3 changes across experimental time points in cell culture and tissue-derived research samples. Storage and handling conditions detailed in the product insert should be observed to preserve reagent activity across multiple experimental runs.