Mouse Tartrate-resistant acid phosphatase type 5 (Acp5) ELISA Kit

Designed for the accurate quantification of Tartrate-resistant acid phosphatase type 5 (ACP5) levels in mouse samples, this Sandwich ELISA Kit from Assay Genie supports bone-related research. ACP5 is an important enzyme involved in bone metabolism, particularly in osteoclast activity and bone resorption, and its dysregulation has been linked to various bone disorders, making it a valuable biomarker for studying bone health and developing therapeutic interventions.

The kit demonstrates a detection range of 0.312-20U/L with a sensitivity of 0.156U/L, an Intra CV of 6.7% and an Inter CV of 8.5%. It is reactive with mouse samples and validated for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. Specificity is directed against natural and recombinant mouse Tartrate-resistant acid phosphatase type 5, with applications in the field of immunology.

According to UniProt (Q05117), the target protein may play a role in the process of bone resorption, with the osteoclastic trap acting on nucleotide tri- and diphosphates with higher affinity compared with other substrates. The protein is localized to the lysosome, has a molecular weight of 36,807 Da, and exists either as a monomer or, after proteolytic processing, as a dimer of two chains linked by disulfide bond(s). For research use only.