Mouse T-cell-specific surface glycoprotein CD28 (Cd28) ELISA Kit

Manufactured by Assay Genie, this Sandwich ELISA Kit is intended for the quantitative detection of mouse T-cell-specific surface glycoprotein CD28 in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. The assay uses a colorimetric detection method with reactivity confirmed in mouse samples and specificity directed against natural and recombinant mouse CD28.

The kit delivers a detection range of 0.625-40ng/mL and a sensitivity of 0.325ng/mL, supporting reproducible quantification in immunology research. It is suited to studies of T-cell activation, immune response regulation, and autoimmune disease models, where CD28 serves as a valuable biomarker.

CD28 is involved in T-cell activation, the induction of cell proliferation and cytokine production, and the promotion of T-cell survival, enhancing IL4 and IL10 production in conjunction with TCR/CD3 ligation and CD40L costimulation. The protein forms a disulfide-linked homodimer, interacts with DUSP14, GRB2, CD80/B7-1 and CD86/B7-2, and is annotated under UniProt P31041 with a molecular weight of 25,243 Da. The kit is for research use only.