Mouse T-box transcription factor TBX3 (Tbx3) ELISA Kit

A sandwich ELISA designed for the precise detection of mouse T-box transcription factor TBX3 (Tbx3) levels. From Assay Genie, this colorimetric kit is intended for research use only and targets natural and recombinant mouse T-box transcription factor TBX3 (synonym: T-box protein 3). It is reactive with mouse samples, including serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids.

Reported performance characteristics include a detection range of 0.156-10ng/mL and a sensitivity of 0.071ng/mL. Intra-assay CV is 7.3% and inter-assay CV is 9.7%. Recovery averages 83% (range 80-89%) for serum and 85% (range 80-91%) for plasma. The kit is validated in the Cancer research area, with subcellular localisation reported as the nucleus. TBX3 is described as a transcriptional repressor involved in developmental processes, probably playing a role in limb pattern formation, and acting as a negative regulator of PML function in cellular senescence. The protein interacts with PML and corresponds to UniProt entry P70324, with a reported molecular weight of 76,949 Da.