Mouse Suppressors Of Cytokine Signaling 3 (SOCS3) ELISA Kit

SOCS3 functions as a critical intracellular feedback inhibitor within the JAK/STAT signaling cascade, dampening cytokine-driven STAT3 activation downstream of IL-6, leptin, and related ligands. This mouse-specific Assay Genie immunoassay enables quantitative measurement of SOCS3 protein levels across multiple specimen types, supporting research into cytokine regulation, innate immunity, and metabolic disease pathways.

Validated for tissue homogenates, cell lysates, and cell culture supernatants, the workflow accommodates both in vivo and in vitro experimental designs. Common applications include investigation of hepatic inflammation, macrophage polarization, insulin resistance, autoimmune models, and cytokine-induced STAT signaling. Reagents are supplied in a microplate format sufficient for 96 individual determinations. Refrigerated storage is recommended; for research use only.