Mouse Succinate Dehydrogenase Complex Subunit C (SDHC) ELISA Kit

The Mouse SDHC ELISA Kit from Assay Genie enables quantitative measurement of succinate dehydrogenase cytochrome b560 subunit, a ~18 kDa integral membrane anchor of mitochondrial respiratory Complex II. SDHC tethers the catalytic SDHA/SDHB dimer to the inner mitochondrial membrane, bridging the Krebs cycle and oxidative phosphorylation by passing electrons from succinate to ubiquinone.

Researchers apply this ELISA to studies of mitochondrial bioenergetics, TCA cycle flux, and Complex II assembly in mouse models. Relevant published applications include paraganglioma-pheochromocytoma syndromes (PGL3), succinate-driven tumor metabolism, and Complex II deficiencies linked to neurodegeneration and metabolic disease. The kit supports research use only workflows with mouse tissue homogenates, complementing western blot and immunohistochemistry approaches targeting mitochondrial markers.