Mouse Stabilin-2 (Stab2) ELISA Kit

A sandwich ELISA designed for the accurate quantification of stabilin-2 levels in mouse serum, plasma, and cell culture supernatants. Manufactured by Assay Genie, the kit offers sensitivity and specificity for reliable, reproducible results across a variety of research applications. The assay detects natural and recombinant mouse Stabilin-2, with the target protein referenced under UniProt Q8R4U0 and a reported molecular weight of 277,532 Da.

Stated performance characteristics include a detection range of 0.312-20ng/mL and a sensitivity of 0.159ng/mL. The kit is suitable for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and is for research use only.

Stabilin-2 functions as a phosphatidylserine receptor that enhances the engulfment of apoptotic cells and as a hyaluronan receptor mediating endocytosis of hyaluronic acid. It also acts as a primary systemic scavenger receptor for ligands including heparin, chondroitin sulfate, dermatan sulfate, acetylated low-density lipoprotein, pro-collagen propeptides, and advanced glycation end products. Dysregulation of stabilin-2 has been implicated in liver fibrosis, atherosclerosis, and autoimmune disorders, supporting its use as a biomarker in studies of inflammation and tissue homeostasis.