Mouse SST (Somatostatin) ELISA Kit (MOES01498)

From Assay Genie, this competitive ELISA kit is designed for the precise measurement of somatostatin (SST) levels in mouse serum, plasma, and cell culture supernatants. It uses a colorimetric detection method based on the Competitive-ELISA principle, in which a biotinylated detection antibody and target antigen in standards or samples compete for binding to antigen pre-coated on the microplate, followed by an Avidin-Horseradish Peroxidase (HRP) conjugate. Substrate development is read at 450 nm ± 2 nm, with colour intensity inversely proportional to antigen concentration.

Reported sensitivity is 4.69 pg/mL and the detection range is 7.81-500 pg/mL, with recovery of 80%-120%. The full assay is completed in 2 h 30 min using a sample volume of 50 μL. The kit specifically recognises Mouse SST in samples, with no significant cross-reactivity or interference observed between Mouse SST and analogues. Reagents are stored at 2-8℃ and the kit is intended for research in cancer, developmental biology, neuroscience, and stem cells.

Somatostatin is a key hormone that inhibits the release of growth hormone and insulin and plays a crucial role in the control of cell growth, neurotransmission, and hormone secretion. Dysregulation of somatostatin is associated with acromegaly, diabetes, and certain neurological disorders, supporting its use as a biomarker for studying these conditions and exploring potential therapeutic interventions.